As diagnosticians we are in a strategic position to look at the performance - or lack thereof - of veterinary products. In the past few years in the course of our work we have investigated instances where the performance of both biological and non-biological products has left something to be desired in terms of safety and efficacy.  

Investigators: D O'Toole

Publications

D O'Toole, L Steadman, M Raisbeck, R Torpy 2004. Myositis, lameness and recumbency following use of water-in-oil adjuvanted vaccines in late-term beef cattle.  J Vet Diagn Invest 17: 23 – 31.

McAllister et al (1995) Myositis, lameness and paraparesis associated with use of an oil-adjuvant bacterin in beef cows. J Am Vet Med Assoc 207: 936 - 938.

O'Toole et al (1995) Iatrogenic compressive lumbar myelopathy and radiculopathy in adult cattle following injection into loin muscle of an adjuvanted bacterin: histopathology and ultrastructure. J Vet Diagn Invest. 7(2):234-244.

Hamar, D.W., Bedwell, C.L., Johnson, J.L., Schultheiss, P.C., Raisbeck, M., Grotelueschen D. M., Williams, E.S.W., O’ Toole, D., Paumer, R. J., Vickers, M.G., Graham, T.J. (1997) Iatrogenic copper tozicoxisis induced by administering copper oxide boluses to neonatal calves. J Vet Diagn Invest 9 (4): 441 – 443

Van Campen H, Woodard L (1997) Fetal infection may not be preventable with BVDV vaccines. J Am Vet Med Assoc 210(4):480