The digital age is influencing all aspects of science,
especially microscopy. The emergence of digital imaging combined with the
use of sophisticated software is making microscopic macro-imaging more
efficient and technologically advanced. Special imaging techniques, which
were once impossible or very difficult with traditional film imaging, are
now achievable and are taking scientific examination and documentation to
the next level.
It is now possible to employ the widely used stereo
dissecting microscope, along with advanced computer software, to perform
special macro-imaging techniques like extended depth of focus (EDF) and
automatic montage. However, these techniques require special hardware that
is often found only on new model microscopes. Many researchers and
scientists already have a dissecting microscope and are without the
resources available to obtain a new one capable of these advanced imaging
techniques. Furthermore, it is difficult and expensive to attach specialized
hardware to older model microscopes.
To overcome these problems, a researcher at the University of
Wyoming’s Zoology and Physiology Microscopy Core Facility has developed a
simple, multi-axial stage for multi-purpose image acquisition that can
easily be attached to any existing dissecting microscope. Some applications
of this multi-axial stage include:
Rotation or tilt for specimen imaging at any angle, including stereo pair imaging with a 12 degree tiling angle. See Figure 1 below.



Z-axis with
a 0.5 mm incremental maker, used for manual focus change and image
acquisition at different focal points for creating an image with extended
depth of focus (EDF). The z-axis can be motorized for more accurate and
automatic z-acquisition. See Figure 2 below.


X-Y stage used for montage. If a specimen is too large to be imaged in one frame, or a small sample needs to be imaged at high magnification, several images can be taken and then stitched together. X-Y stage used to move or center the specimen without touching it. See Figure 3 below.


If you would like to learn more about this patent-pending multi-axial stage for stereo dissecting microscopes and how your company may apply it in commercial situations, please contact Davona Douglass at the University of Wyoming Research Products Center. We would be pleased to share further details.
Research Products Center
Dept. 3672
1000 E. University Ave.
Laramie, WY 82071
(307)766-2520
Fax: (307) 766-2530
e-mail: WyomingInvents@uwyo.edu