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University of Wyoming
Franco Basile

Franco Basile
Associate Professor
Analytical Chemistry

B.S. in Chemistry, 1985, University of Wisconsin at Eau Claire
Ph.D. in Analytical Chemistry, 1992, Purdue University
Postdoctoral Fellow, Colorado School of Mines


basile@uwyo.edu • PS 311 • (307) 766-4376

 

The area of research of the Basile Group at the University of Wyoming is Analytical Chemistry with a focus on the application of Mass Spectrometry to analyze a variety of biological and environmental samples. Specifically, our research is aimed at developing rapid biological sample preparation techniques suitable for proteomic measurements that can be implemented in field-portable instrumentation. These techniques are based on the use of non-enzymatic steps to lyse/digest biological samples to a stage that is suitable for MS analysis. Our laboratory pioneered the use of microwave heating for non-enzymatic digestion of proteins at aspartic acid and disulfide bonds and other non-enzymatic site-specific techniques that reduce digestion times from hours to seconds.

Research conducted by the Basile Group also focuses on alternative energy sources like methane production from bacteria residing in coal-bed deposits. Research in this area is geared at performing broad spectrum analysis of soluble matter in coal sludge and proteomic analysis of methanogenic bacteria.
 

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